DUPLEX 5/80 – Amlodipine
Amlodipine blocks calcium channels in the blood vessels and as a result, causes them to relax. Angiotensin II is a substance produced by the body that causes blood vessels to constrict, thus increasing the blood pressure. Valsartan blocks the effect of angiotensin II. As a result of both mechanisms, the blood vessels relax and blood pressure is lowered. Duplex is used to treat high blood pressure in patients with high blood pressure that did not decrease following the use of amlodipine or valsartan alone. If high blood pressure persists for a long time, damage to the blood vessels of the brain, heart, and kidneys, which may result in a stroke, heart failure, or kidney failure can occur. Lowering the blood pressure to normal levels reduces the risk of developing these problems. If you have any questions about how Duplex works or why this medicine has been prescribed for you, refer to your doctor.